TRANSLATIONAL PRURITUS RESEARCH
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Recent Project-related Publications

January 2021.

  • Pereira MP, Wiegmann H, Agelopoulos K, Ständer S. Neuropathic itch: routes to clinical diagnosis. Front Med 2021, in press.
  • Ruppenstein A, Limberg M, Loser K, Kremer AE, Homey B, Raap U  (2021). Involvement of neuro-immune interactions in pruritus with special focus on receptor expressions . Front. Med. 8:627985. doi: 10.3389/fmed.2021.627985
  • Solinski HJ, Rukwied R. Electrically Evoked Itch in Human Subjects. Front Med (Lausanne). 2021 Jan 20;7:627617. doi: 10.3389/fmed.2020.627617. PMID: 33553220; PMCID: PMC7855585
  • Wolf K, Kühn H, Boehm F, Gebhardt L, Glaudo M, Agelopoulos K, Ständer S, et al. A Group of Cationic Amphiphilic Drugs Activates MRGPRX2 and Induces Scratching Behavior in Mice. J Allergy Clin Immunol 2021, in press.

October 2020

  • Kühn H, Kolkhir P, Babina M, Düll M, Frischbutter S, Fok JS, Jiao Q, Metz M, Scheffel J, Wolf K, Kremer AE, Maurer M. Mas-related G protein-coupled receptor X2 and its activators in dermatologic allergies. J Allergy Clin Immunol. 2021 Feb;147(2):456-469. doi: 10.1016/j.jaci.2020.08.027. Epub 2020 Oct 15. PMID: 33071069.
  • Rukwied R, Schnakenberg M, Solinkski HJ, Schmelz M, Weisshaar E. Transcutaneous Slowly Depolarizing Currents Elicit Pruritus in Patients with Atopic Dermatitis. Acta Derm Venereol. 2020 Oct 28;100(17):adv00302. doi: 10.2340/00015555-3658. PMID: 33026094.

July  2020

  • ​Mettang T, Kremer AE. Kniffelige Fälle – Wann bringt die Labordiagnostik eine Lösung? [Brain teasers in pruritus-when laboratory tests will guide you]. Hautarzt. 2020 Jul;71(7):500-505. German. doi: 10.1007/s00105-020-04615-1. PMID: 32468294.



May 2020

​
  • Schmelz M. Pruritus – ein weiter Weg von der Neurophysiologie zur Klinik [Pruritus-a long journey from neurophysiology to the clinic] [published online ahead of print, 2020 May 28]. Hautarzt. 2020;10.1007
  • Rukwied R, Thomas C, Obreja O, et al. Slow depolarizing stimuli differentially activate mechanosensitive and silent C-nociceptors in human and pig skin [published online ahead of print, 2020 May 4]. Pain. 2020;10.1097

February 2020

  • Kühn H,  Kappes L, Wolf K, Gebhardt L, Neurath M, Reeh P, Fischer M, Kremer AE. Complementary roles of murine NaV1.7, NaV1.8 and NaV1.9 in acute itch signalling. Scientific Reports 2020. 10:2326

January 2020:


  • Guseva D, Rüdrich U, Kotnik N, Gehring M, Patsinakidis N, Agelopoulos K, Ständer S, Homey B, Kapp A, Gibbs BF, Ponimaskin E, Raap U. Neuronal branching of sensory neurons is associated with BDNF-positive eosinophils in atopic dermatitis. Clin Exp Allergy. 2020 Jan 10. doi: 10.1111/cea.13560.
  • Kremer AE, Mettang T, Weisshaar E. Non-dermatological Challenges of Chronic Itch. Acta Derm Venereol. 2020 Jan 7;100(2):adv00025. doi: 10.2340/00015555-3345. PMID: 31940045.

December 2019:

  • ​Kremer AE. What are new treatment concepts in systemic itch? Exp Dermatol. 2019 Dec;28(12):1485-1492. doi: 10.1111/exd.14024. Epub 2019 Sep 9. PMID: 31452276.

November 2019:

  • Pereira MP, Derichs L, Meyer Zu Hörste G, Agelopoulos K, Ständer S. Generalized chronic itch induced by small-fiber neuropathy: clinical profile and proposed diagnostic criteria. J Europ Acad Dermatol Venereol 2019, [Epub ahead of print]. doi: 10.1111/jdv.16151

September 2019:

  • Agelopoulos K, Rülander F, Dangelmaier J, Lotts L, Osada N, Metze D, Luger TA, Loser K, Ständer S. Neurokinin 1 receptor antagonists exhibit peripheral effects in prurigo nodularis including reduced ERK1/2 activation. J Eur Acad Dermatol Venereol 2019 
  • Pereira MP, Zeidler C, Storck M, Agelopoulos K, Philipp-Dormston WG, Zink A, Ständer S. Challenges in Clinical Pruritus Research and Care. Acta Derm Venereol 2020; 100(2):adv00028.
  • Süer A, Soto Rey, I, Storck M, Pereira MP, Agelopoulos K, Ständer S, Dugas M, Bruland P. Standardbasierte vernetzte IT-Infrastruktur zur multizentrischen und multidisziplinären Verwaltung von Forschungsdaten – Integration im Rahmen der DFG-geförderten Forschergruppe „PruSearch. Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie. 64. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS). Dortmund, 08.-11.09.2019. Düsseldorf: German Medical Science GMS Publishing House; 2019. DocAbstr. 179 . doi: 10.3205/19gmds173

August 2019:.

  • Kremer AE, Mettang T. Pruritus bei systemischen Erkrankungen : Häufiges und Seltenes [Pruritus in systemic diseases : Common and rare etiologies]. Internist (Berl). 2019 Aug;60(8):814-820. German. doi: 10.1007/s00108-019-0637-0. PMID: 31243493.​

July 2019:

  • Düll MM, Kremer AE. Treatment of Pruritus Secondary to Liver Disease. Curr Gastroenterol Rep. 2019 Jul 31;21(9):48. doi: 10.1007/s11894-019-0713-6. PMID: 31367993.
  • Mueller SM, Schmid Y, Navarini A, Manjaly Thomas ZR, Pfleiderer B, Kraehenbuehl S. Sex differences in the pharmacology of itch therapies - a narrative review Curr Opin Pharmacol, 2019, 46:122–142. https://doi.org/10.1016/j.coph.2019.05.008
  • Pereira MP, Agelopoulos K, Köllner J, Neufang G, Schmelz M, Ständer S. Selective nerve fiber activation in patients with chronic generalized pruritus: hint for central sensitization? Acta Derm Venereol 2019 https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3261
  • Pogatzki-Zahn EM, Pereira MP, Cremer A, Zeidler C, Dreyer T, Riepe C, Wempe C, Lotts T, Segelcke D, Ringkamp M, Kremer AE, Agelopoulos K, Ständer S. Peripheral sensitisation and loss of descending inhibition is a hallmark of chronic pruritus. J Invest Dermatol J Invest Dermatol 2020; 140(1):203-211.e4.
  • Schmelz M. Itch Processing in the Skin. Front Med (Lausanne). 2019;6:167. Published 2019 Jul 19. doi:10.3389

June 2019:

  • Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases. Gibbs BF, Patsinakidis N, Raap U. Front Immunol. 2019 Jun 21;10:1383. doi: 10.3389/fimmu.2019.01383. eCollection 2019. Review.
  • Hidding J, Agelopoulos K, Pereira MP, et al. Sensory Qualities Point to Different Structural and Functional Skin Patterns in Chronic Pruritus Patients. A Translational Explorative Study. Acta Derm Venereol. 2019;99(7):668-674

May 2019:

  • Ständer S. How to define chronic pruritus – symptom or disease? Exp Dermatol 2019, https://onlinelibrary.wiley.com/doi/full/10.1111/exd.13953
  • Steinhoff M, Oaklander AL, Szabó IL, Ständer S, Schmelz M. Neuropathic itch. Pain 2019;160 Suppl 1:S11-S16 https://insights.ovid.com/pubmed?pmid=31008844
  • Robering JW, Gebhardt L, Wolf K, Kühn H, Kremer AE*, Fischer MJM*. Lysophosphatidic acid activates satellite glia cells and Schwann cells. Glia. 2019 May;67(5):999-1012. *contributed equally (IF2017: 6,2)

April 2019:

  • Baumann KY, Church MK, Clough GF, et al. Skin microdialysis: methods, applications and future opportunities-an EAACI position paper. Clin Transl Allergy. 2019;9:24. Published 2019 Apr 10. doi:10.1186
  • Hidding J, Agelopoulos K, Pereira MP, et al. Sensory Qualities Point to Different Structural and Functional Skin Patterns in Chronic Pruritus Patients. A Translational Explorative Study. Acta Derm Venereol. 2019;99(7):668-674

March 2019:

  • Tsianakas A, Nippe N, Hamper CM, Cordes AF, Zeidler C, Schmelz M, Ständer S. Exploratory Study of Intracutaneous Histamine Stimulation in Patient Populations with Chronic Pruritus. Acta Derm Venereol. 2019; 99: 291-297. doi: 10.2340/00015555-3078. https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3078

December 2018:

  • Pereira MP, Mittal A, Ständer S. Current treatment strategies in refractory chronic pruritus. Curr Opin Pharmacol 2018; 46: 1-6 https://www.sciencedirect.com/science/article/pii/S1471489218301280?via%3Dihub
  • Steinhoff M, Schmelz M, Szabó IL, Oaklander AL. Clinical presentation, management, and pathophysiology of neuropathic itch. Lancet Neurol. 2018;17(8):709-720
  • Meyer NH, Gibbs B, Schmelz M, Homey B, Raap U. Neurophysiologie des atopischen Pruritus [Neurophysiology of atopic pruritus]. Hautarzt. 2018;69(3):204-209
  • Home
  • About
    • Disclaimer
  • Objectives
  • Projects
    • Project 1
    • Project 2
    • Project 3
    • Project 4
    • Project 5
    • Project 6
    • Project 7
    • Project Z
    • Independent Review and Support Committee
    • Internal
  • Activities and News
    • Research Consortium Meeting in Münster
    • 4th Young Scientist + Gender Equity Webinar
    • 3rd Young Scientists Forum
    • Project-related Publications
  • Young Scientists Forum
  • Contact
  • Research consortium meeting in Münster
  • Research Consortium Meeting