Recent Project-related Publications

May 2020

• Schmelz M. Pruritus – ein weiter Weg von der Neurophysiologie zur Klinik [Pruritus-a long journey from neurophysiology to the clinic] [published online ahead of print, 2020 May 28]. Hautarzt. 2020;10.1007
  
• Rukwied R, Thomas C, Obreja O, et al. Slow depolarizing stimuli differentially activate mechanosensitive and silent C-nociceptors in human and pig skin [published online ahead of print, 2020 May 4]. Pain. 2020;10.1097
  

February 2020

• Helen Kühn, Leonie Kappes, Katharina Wolf, Lisa Gebhardt, Markus F. Neurath, Peter Reeh, Michael J. M. Fischer, Andreas E. Kremer. Complementary roles of murine NaV1.7, NaV1.8 and NaV1.9 in acute itch signalling. Scientific Reports 2020. 10:2326

January 2020:

• Guseva D, Rüdrich U, Kotnik N, Gehring M, Patsinakidis N, Agelopoulos K, Ständer S, Homey B, Kapp A, Gibbs BF, Ponimaskin E, Raap U. Neuronal branching of sensory neurons is associated with BDNF-positive eosinophils in atopic dermatitis. Clin Exp Allergy. 2020 Jan 10. doi: 10.1111/cea.13560.
  

November 2019:

• Pereira MP, Derichs L, Meyer Zu Hörste G, Agelopoulos K, Ständer S. Generalized chronic itch induced by small-fiber neuropathy: clinical profile and proposed diagnostic criteria. J Europ Acad Dermatol Venereol 2019, [Epub ahead of print]. doi: 10.1111/jdv.16151
  

September 2019:

• Agelopoulos K, Rülander F, Dangelmaier J, Lotts L, Osada N, Metze D, Luger TA, Loser K, Ständer S. Neurokinin 1 receptor antagonists exhibit peripheral effects in prurigo nodularis including reduced ERK1/2 activation. J Eur Acad Dermatol Venereol 2019 in press

• Pereira MP, Zeidler C, Storck M, Agelopoulos K, Philipp-Dormston WG, Zink A, Ständer S. Challenges in Clinical Pruritus Research and Care. Acta Derm Venereol 2020; 100(2):adv00028.
  
• Süer A, Soto Rey, I, Storck M, Pereira MP, Agelopoulos K, Ständer S, Dugas M, Bruland P. Standardbasierte vernetzte IT-Infrastruktur zur multizentrischen und multidisziplinären Verwaltung von Forschungsdaten – Integration im Rahmen der DFG-geförderten Forschergruppe „PruSearch. Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie. 64. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS). Dortmund, 08.-11.09.2019. Düsseldorf: German Medical Science GMS Publishing House; 2019. DocAbstr. 179 . doi: 10.3205/19gmds173
  

July 2019:

• Mueller SM, Schmid Y, Navarini A, Manjaly Thomas ZR, Pfleiderer B, Kraehenbuehl S. Sex differences in the pharmacology of itch therapies - a narrative review Curr Opin Pharmacol, 2019, 46:122–142. https://doi.org/10.1016/j.coph.2019.05.008
• Pereira MP, Agelopoulos K, Köllner J, Neufang G, Schmelz M, Ständer S. Selective nerve fiber activation in patients with chronic generalized pruritus: hint for central sensitization? Acta Derm Venereol 2019 https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3261
• Pogatzki-Zahn EM, Pereira MP, Cremer A, Zeidler C, Dreyer T, Riepe C, Wempe C, Lotts T, Segelcke D, Ringkamp M, Kremer AE, Agelopoulos K, Ständer S. Peripheral sensitisation and loss of descending inhibition is a hallmark of chronic pruritus. J Invest Dermatol J Invest Dermatol 2020; 140(1):203-211.e4.
  
• Schmelz M. Itch Processing in the Skin. Front Med (Lausanne). 2019;6:167. Published 2019 Jul 19. doi:10.3389
• Yosipovitch G, Misery L, Proksch E, Metz M, Ständer S, Schmelz M. Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions. Acta Derm Venereol. 2019;99(13):1201-1209. doi:10.2340/00015555-3296
  
  

June 2019:

• Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases. Gibbs BF, Patsinakidis N, Raap U. Front Immunol. 2019 Jun 21;10:1383. doi: 10.3389/fimmu.2019.01383. eCollection 2019. Review.
  

• Hidding J, Agelopoulos K, Pereira MP, et al. Sensory Qualities Point to Different Structural and Functional Skin Patterns in Chronic Pruritus Patients. A Translational Explorative Study. Acta Derm Venereol. 2019;99(7):668-674
  

May 2019:

• Ständer S. How to define chronic pruritus – symptom or disease? Exp Dermatol 2019, https://onlinelibrary.wiley.com/doi/full/10.1111/exd.13953
• Steinhoff M, Oaklander AL, Szabó IL, Ständer S, Schmelz M. Neuropathic itch. Pain 2019;160 Suppl 1:S11-S16 https://insights.ovid.com/pubmed?pmid=31008844
• Robering JW, Gebhardt L, Wolf K, Kühn H, Kremer AE*, Fischer MJM*. Lysophosphatidic acid activates satellite glia cells and Schwann cells. Glia. 2019 May;67(5):999-1012. *contributed equally (IF2017: 6,2)
  

April 2019:

• Baumann KY, Church MK, Clough GF, et al. Skin microdialysis: methods, applications and future opportunities-an EAACI position paper. Clin Transl Allergy. 2019;9:24. Published 2019 Apr 10. doi:10.1186
• Hidding J, Agelopoulos K, Pereira MP, et al. Sensory Qualities Point to Different Structural and Functional Skin Patterns in Chronic Pruritus Patients. A Translational Explorative Study. Acta Derm Venereol. 2019;99(7):668-674
  

March 2019:

• Tsianakas A, Nippe N, Hamper CM, Cordes AF, Zeidler C, Schmelz M, Ständer S. Exploratory Study of Intracutaneous Histamine Stimulation in Patient Populations with Chronic Pruritus. Acta Derm Venereol. 2019; 99: 291-297. doi: 10.2340/00015555-3078. https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3078
  

December 2018:

• Pereira MP, Mittal A, Ständer S. Current treatment strategies in refractory chronic pruritus. Curr Opin Pharmacol 2018; 46: 1-6 https://www.sciencedirect.com/science/article/pii/S1471489218301280?via%3Dihub
  
• Steinhoff M, Schmelz M, Szabó IL, Oaklander AL. Clinical presentation, management, and pathophysiology of neuropathic itch. Lancet Neurol. 2018;17(8):709-720
  
• Meyer NH, Gibbs B, Schmelz M, Homey B, Raap U. Neurophysiologie des atopischen Pruritus [Neurophysiology of atopic pruritus]. Hautarzt. 2018;69(3):204-209